Ketamine has the advantage of fast action compared to traditional antidepressants, which often take weeks to reach full effectiveness. Many patients report noticeable mood improvements within hours to days of a ketamine session. Clinical studies indicate that, with continued treatment, ketamine can provide both immediate and sustained reductions in depressive symptoms, offering a valuable option for those who haven’t benefited from conventional medications.

Ketamine is administered in a clinic under the supervision of a healthcare provider and cannot be taken at home. During each session, you’ll receive a single injection of ketamine, after which you’ll be monitored by clinic staff for about one to two hours. Initial treatment often consists of two sessions per week for the first month, then weekly or bi-weekly as maintenance, depending on your response and individual treatment plan discussed with your psychiatrist.

Common side effects include mild sedation, dissociation, and a “dreamlike” feeling that typically wears off within an hour or two. This observation period is required for safety and to allow side effects to subside before leaving the clinic. Other possible side effects include nausea, dizziness, increased blood pressure, and fatigue. Patients are advised not to drive for the remainder of the day after receiving treatment.