Although ketamine’s mechanism of action (MOA) as an anesthetic has been extensively studied, the MOA of esketamine’s antidepressant effect is poorly understood. Suggested mechanisms include improved brain plasticity via the stimulation of brain-derived neurotropic factor (BDNF) production and activation of the mammalian target of rapamycin. – National Library of Medicine (2019) Esketamine is a medication
November 14, 2023
